Green M, Chen A, Nostro MC, d’Souza S, Schaniel C, Lemischka IR, Gouon-Evans V, Keller G, Snoeck HW. (2011). Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells. Nat. Biotechnol., 29:267-272.
Huang SX, Islam MN, O’Neill J, Hu Z, Yang Y-Y, Chen Y-W, Green MD, Mumau M, Vunjac-Novakovic G, Bhattacharya J, Snoeck HW. (2014) Highly efficient generation of lung and airway epithelial cells from human pluripotent stem cells. Nat Biotechnol., 32:84-91.
Huang SX, Green M, Toste A, Mumau M, Chen YW, Snoeck HW (2015) Protocol of for the generation of lung and airway epithelial cells from human pluripotent stem cells. Nat. Protocols, 10:413-425.
Ciancanelli M, Huang SX, Luthra P, Garner H, ITan Y, Volpi S, Trouillet C, Schmolke M, Isrealsson E, Herman M, Hermesh T, Lorenzo L, Albrecht RA, Leung LW, Okada S, Picard C, Ringuier B, Troussier F, Chaussabel D, Abel L, Pellier I, Notarangelo LD, Garcai-Sastre A, Basler CF, Geissmann F, Zhang SY, Snoeck HW, Casanova JL (2015) Impaired innate and intrinsic IFNα/β amplification underlies life-threatening influenza in human inherited IRF7 deficiency. Science, 348:448-553.
Chen YW, Huang SX, Rodrigues Toste de Carvalho AL, Ho SH, Islam MS, Volpi S, Notarangelo LS, Ciancanelli M, Casanova LS, Bhattacharya J, Liang AF, Palermo LM, Porotto M, Moscona A, Snoeck HW. (2017) A three-dimensional model of human lung development and disease from pluripotent stem cells. Nat Cell Biol., 19:542-549.
Dorrello NV, Guenthart BA, O'Neill JD, Kim J, Cunningham K, Chen YW, Biscotti M, Swayne T, Wobma HM, Huang SXL, Snoeck HW, Bacchetta M, Vunjak-Novakovic G. (2017) Functional Vascularized Lung Grafts for Lung Bioengineering. Sci Adv. 3(8):e1700521.
Toste de Carvalho, AL, Liu HY, Strikoudis A, Dantas TJ, Chen YW, Vallee RB, Correia-Pinto J, Snoeck HW. (2019) Glycogen Synthase Kinase 3 induces multilineage maturation of lung progenitors derived from human pluripotent stem cells in 3D culture. Development Jan 22:146(2). doi: 10.1242/dev.171652.
Chen H, Poran A, Unni A, Huang XL, Elemento E, Snoeck HW, Varmus H. (2019). Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells. J Exp Med 4;216(3):674-687.
Porotto M, Ferren M, Chen Y-W, Siu Y, Makhsous N, Rima B, Briese T, Greninger AL, Snoeck HW, Moscona A. (2019) Authentic modeling of human respiratory virus infection in human pluripotent-derived lung organoids. MBIO,10:3 pii: e00723-19.
Strikoudis A, Cieslak A, Loffredo L, Chen YC, Patel N, Saqi A, Lederer DJ, Snoeck HW. (2019). Modeling of fibrotic lung disease using 3D organoids derived from human pluripotent stem cells. Cell Reports 27(12):3709-3723.e5.
Lim HK, Huang SXL, Chen J, Kerner G, Gilliaux O, Bastard P, Dobbs K, Hernandez N, Goudin N, Hasek ML, García Reino EJ, Lafaille FG, Lorenzo L, Luthra P, Kochetkov T, Bigio B, Boucherit S, Rozenberg F, Vedrinne C, Keller MD, Itan Y, García-Sastre A, Celard M, Orange JS, Ciancanelli MJ, Meyts I, Zhang Q, Abel L, Notarangelo LD, Snoeck HW, Casanova JL, Zhang SY. (2019) Severe Infuenza infection in children with inherited TLR3 deficiency. J Exp Med 216:2038-2056.
Basil MC, Katzen J, Engler AE, Gou M, Herriges MJ, Kathiriya JJ, Windmueller R, Ysais AB, Zacharias WJ, Chapman HA*, Kotton DN*, Rock JR*, Snoeck HW*, Vunjak-Novakovic G*, Whitsett JA*, Morrisey EE* (2020). The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future. Cell Stem Cell 26:481-501 (*senior authors).
De Carvalho AL, Liu HY, Chen, YW, Porotto M, Moscona A, Snoeck HW. (2021). The in vitro multi-lineage differentiation and maturation of lung and airway cells from human pluripotent stem cell-derived lung progenitors in 3D. Nat Protocols 16:1802-1829.
Matkovic Leko I,* Schneider RT,* Thimraj TA,* Schrode N, Daniel Beitler D, Liu HY, Beaumont K, Chen YW,+ Snoeck HW.+ (2023) A distal lung organoid model to study interstitial lung disease, viral infection and human lung development. Nat Protocols 18:2283-2312. (* and + equal contribution).
Pezet MG, Torres JA, Thimraj TA, Matkovic Leko I, Schrode N, Murray JW, Saqi A, Beaumont, CG, Snoeck, HW. (2025) Human respiratory airway progenitors derived from pluripotent cells generate alveolar epithelial cells and model pulmonary fibrosis. Nat Biotechnol doi:10.1038/s41587-025-02569-0. Epub ahead of print.
Snoeck HW. (2025) New insights into the pathogenesis of fibrotic interstitial lung diseases. Eur Resp Journal, in press.
https://www.youtube.com/channel/UCe82I_oZrW6goxV8elXe6tw
Multiple patent applications cover the generation of organoids and engrafting cells from human pluripotent stem cells and protect the generation and use of the cells. These have been or are in the process of being nationalized in the US, EPO, Israel, Japan, and China.